Each game genre is defined by the topic of game you select. For each new game you create you will have to decide what topic you are going to make. (i.e. - Fantasy RPG, Space Simulation, Aliens Action, etc..)
List of Game TopicsEdit
As you go through your game you can research new topics to pair with your genres. These pairings will create your Game Combos.
Starting Topic VariationEdit
As of the moment it appears that with each new game company that you create, the order in which you can unlock games will vary. This appears to be true outside of the base 8 which currently remain set allowing you a strong baseline with which to start your company.